I am a biophysicist with extensive experience in working with
custom-built microscopes and quantitative analysis of single-molecule data. This
includes a strong command of statistical data analysis, biochemistry skills such
as protein and DNA labeling and expertise in controlling dye photophysics. I
am currently working at the EPFL, extending my quantitative microscopy
expertise to 3D super-resolution and phase imaging. As a Horizon 2020 Marie
Sklodowska Curie fellow, I aim at bridging neurobiology and life science with
advanced microscopy and image analysis for the direct monitoring of Parkinson
compromised neurons to uncover the underlying molecular mechanism.
A primary hippocampal neuron from mice treated with alpha-synuclein fibrils.
The second order SOFI image (left) shows newly formed alpha-synuclein
aggregates with color-coded z-position. The neuron cell body can be seen in
a 2d phase image slice (right). The center image shows an overlay of both
images. Both images were taken in a single multi-plane microscope in the lab
of Prof. T. Lasser in collaboration with the group
of Prof. H. Lashuel.
A unique way of investigating the photophysics of conjugated polymers by
looking at the statistics of photon emission. The plot show the changing
emitter number and brightness of a single poly(3-hexylthiophene) chain over
time. The data was taken during my doctorate in the group of Prof. D.-P.
in collaboration with the group of Prof. J. Lupton. DOI: